An Introduction to Functional MRI

Summary of the Course

Logistics Issues

Who are we?

Outline for Today

What is fMRI?

Functional Magnetic Resonance Imaging

Why do Neuroimaging?

Slide 9

Successes of Functional Imaging

Why Image Brain Function?

Mapping Cognition to the Brain

Clinical Uses of FMRI

Slide 14

Clinical Uses of FMRI

Development

History of fMRI

Timeline of MR Imaging

Rabi and the Measurement of the Nuclear Magnetic Moment (19

Discovery of Nuclear Magnetic Resonance Absorption (1946)

Timeline of MR Imaging

Early Uses of NMR

The First ZMR NMR Image

Early Human MR Images (Damadian)

Slide 25

Timeline of MR Imaging

Physiology (BOLD Contrast)

Using MRI to Study Brain Function

Growth in fMRI : Published Studies

Key Concepts

Key Concepts

Contrast: Anatomical

Contrast: Functional

Spatial Resolution: Voxels

Spatial Resolution: Examples

Temporal Resolution

Functional Resolution

Slide 38

MRI Scanners

Slide 40

Slide 41

Main Components of a Scanner

Slide 43

Shimming Coils

Slide 45

Pulse Sequences

MRI Safety

"Hospital Nightmare"

MR Incidents

Issues in MR Safety

Possible Effects of Magnetic Fields

Risks of MRI

Slide 53

Projectile Effects: External

Radiofrequency Energy

Projectile/Torsion Effects: Internal

Acoustic Noise

Gradient Field Changes (dB/dt)

Claustrophobia

Quenching

Scanner Tour