Allen W. Song, Ph.D.Professor of Radiology, Psychiatry, Neurobiology and BME, Duke University
Director, Duke - UNC Brain Imaging and Analysis Center
Ph.D., 1995, Medical College of Wisconsin (Biophysics)
The acquisition methodology, processing strategies and contrast mechanism for functional MRI. Additional interests include the application of the improved acqusition methods to study motor sequence learning and language processing.
The research in this lab is concerned with the advancement of fMRI data acquisition methods that includes the development of real-time imaging using echo-planar and spiral data acquisition with high-order shimming control, development of robust and reliable single-shot image acquisition methods and optimization of the acquisition methods for improved functional sensitivity and specificity.
Our lab is also focused on understanding the contrast mechanism of the functional MRI, which includes the source localization of the functional signal using the blood oxygenation level dependent contrast and development of alternative contrast mechanisms that are more directly linked to the neuronal activities.
Additional effort is invested in applying and validating the developed methods to study human motor sequence learning and language processing.
Truong, T.-K., Song, A. W., Single-Shot Z-Shimmed Sensitivity-Encoded Spiral-In/Out Imaging for fMRI with Reduced Susceptibility Artifacts, Magn. Reson. Med. 59(1) 221-7, 2008.
Song, AW, Truong, TK, Woldorff, MG, Dynamic imaging of small electrical activity, in Dynamic Brain Mapping, Humana Press, 2008.
Truong, T.-K., Avram, A., Song, A. W., Lorentz effect imaging of ionic flow, J. Magn. Reson. 191(1), 93-9, 2008.
Truong, T.-K., Chen, B., Song, A. W., Integrated SENSE DTI with correction of susceptibility- and eddy current-induced geometric distortions, NeuroImage 40(1), 53-8, 2008.
Harshbarger, T. B., Song, A. W., Differentiating Sensitivity of Post-stimulus Undershoot Under Diffusion Weighting: Implication of Vascular and Neuronal Hierarchy, PLOS One, 2008 (in press).